The International Space Station (ISS) has been at the forefront of the extraterrestrial fallout. Dmitry Rogozin, the controversial head of Russian space agency Roscomos, warned last week that sanctions threatened the very existence of the lab: His ominous rebuke brought attention to Russia’s crucial role in the project. The country controls a propulsion system that keeps the ISS in orbit. Without it, the satellite could slowly fall toward the atmosphere. Rogozin may be making idle threats, but there are growing fears that the ISS now faces an early end. This is merely one way that the war has touched outer space. Russia has also decided to stop supplying rocket engines to the US. The move will end a partnership that’s lasted for decades. “Let them fly on something else, their broomsticks, I don’t know what,” Rogozin said last week. In further retaliation for sanctions, Moscow has halted cooperation with Europe on launches from a spaceport in French Guiana, ended joint experiments with Germany on the ISIS, and excluded the US from a joint mission to Venus. Roscosmos has also lost one of its biggest commercial clients: the satellite company OneWeb. The British firm has suspended future launches from Russia’s cosmodrome in Kazakhstan after dismissing an ultimatum to cut ties with the UK government. These problems pale when compared to the human tragedies unfolding in Ukraine. Yet they show that the fragility of our interconnected world expands beyond Earth. Ultimately, the biggest victim will likely be Russia’s commercial space sector. After rivaling NASA during the Soviet era and then entering an age of cooperation, the industry faces an uncertain future.